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Tc-99m Myoview Gated Rat Heart

Univ. of Ottawa Heart Institute | Rat, SPECT only, Dynamic/Gated, Tc-99m

		Comments
		A rat was injected with ~75 MBq (2 mCi) of Tc-labeled Myoview and imaged 30 minutes post-injection for 1 hour. The rat was anesthetized using Isofluorane and exhibited a stable heart rate of ~250 BPM. Rejection rate was near zero and only a slight decrease in heart rate was observed (and adjusted for) over the course of the acquisition. Image courtesy of the University of Ottawa Heart Institute. [Tracer Details]
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Dynamic Mouse Tumor (In-111, movie)

Queen Mary's, London | Mouse, SPECT/CT, Dynamic/Gated, In-111

		Comments
		Bioscan's Image of the Month May: A nude mouse with a pancreatic tumor on its right shoulder. Injected with an 30 MBq (0.8 mCi) of In-111 labeled monomer. Scan range - 35.4mm (just the heart and the tumor were scanned). In total 24 scans, just below 5 minutes each, where performed, summing up to a 2 hour acquisition time. By courtesy of Ciara Finucane (aka SU1). Centre for Cancer Imaging, Barts and The London Queen Mary's School of Medicine and Dentistry London
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I-131 High Energy Mouse Tumor Scan

Molecular Insight Pharmaceutical | Mouse, I-131

		Comments
		Male, NCR-Nude mouse bearing SKMEL3 tumor on left flank. Special apertures used to shield high energy (365 keV) photons of I-131 and advanced reconstruction software used to produce artifact free, high-resolution images. Injected dose only 87 µCi (3 MBq) of I-131 MIP-1145 i.v. as treatment of melanoma. Imaged 24 hours post injection, 80 minutes total acquisition time, due to very low activity. Imaged at the University of New Mexico.
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Rabbit SPECT Scan (In-111, parallel hole collimation)

University of New Mexico | Other Species, SPECT only, In-111

		Comments
		2.6 mCi of In-111 Dotatoc was injected into a 1.5 kg, male rabbit. An 18-minute acquisition was started 5 minutes post injection using an LEUHR collimator on a NanoSPECT/CT. Reconstructions were performed with the Scivis ReSPECT parallel-hole reconstruction software.
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Brain Perfusion of a Cat

Ghent University | Other Species, SPECT only, Tc-99m

		Comments
		The HiSPECT system was employed on a 3-headed Trionix camera to image Tc-99m MDP perfusion in a cat brain.
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Mouse Bone/Thyroid Dual-Isotope Scan (Fusion, Tc-99m, I-123)

University of New Mexico | Mouse, SPECT/CT, Dual-Isotope, Tc-99m, I-123

		Comments
		As published by the Molecular Imaging Center for Excellence newsletter, SNM publication Volume 2, 2008-1: Maximum Intensity Projection (MIP) of a dual-isotope (Tc-99m and I-123) SPECT/CT mouse study. All combinations of fusions of CT with Tc-99m- and I-123-SPECT are shown here. Please note in particular, that the energy resolution of the NanoSPECT is good enough to resolve Tc-99m (140.5 keV) and I-123 (159.0 keV) while still providing the high sensitivity. Injected activities: Tc-99m/MDP: 1mCi I123/LabeledCompound: 200 uCi Scan times: CT : 7.5 min SPECT: 40 min (both isotopes imaged simultaniously) Original publication: 2007-02-26 Animated movie is available here [87].
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PET-CT Mouse FDG Scan (MIP movie)

University of New Mexico | Mouse, PET

		Comments
		This mouse was measured in the CT of a NanoSPECT/CT (45 kVp, 180 prj, 1s exposure, 6 minute acquisition) and then transferred to a small-animal PET system, where it was measured 30 minutes post injection of 322 µCi FDG in 110µl for 30 minutes (1 bed position). Thanks to the dedicated Minerve animal handling system, which can be mounted on both systems, both modalities could be registered easily in the InVivoScope post-processing software. Special Thanks to Ben Gershman for the co-registration.
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Mouse Skull, high resolution (volume rendering)

SPECT-CT.com | Mouse, CT only

		Comments
		Volume rendering of a mouse skull. 360 prj, 1s exposure time, full 50µm resolution. Low transparencies for bone. Same study with low bone opacity: [109].
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PC-3 Fibular Destruction (Volume rendering, Movie)

OSSKI, Hungary | Mouse, CT only

		Comments
		The destruction in the fibular bone is clearly visible three weeks post injection of 5 million PC-3 cells into the region. Circular CT, using 360 projections at 65 kVp and 123µA, 89 mAs. By courtesy of Dr. Domokos Máthé.
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Contrast Enhanced CT (Volume rendering, Fenestra)

Singapore Bioimaging Consortium | Mouse, CT only, Enhanced CT

		Comments
		Example of contrast enhanced CT using Fenestra contrast agent in a mouse.
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