A cohort of ferrets was induced with the flu in an attempt to visualize uptake of radiotracer in the sinuses. In this trial experiment 590uCi of In-111 (green) labeled with an inflammation targeting agent were injected. A fast, 7-minute CT acquisition was acquired over a 230mm scan range followed by a 20-minute SPECT acquisition. In-111 uptake in the trachea, heart, and lymphatic regions is clearly visible. Note also the striations visible in the ferret's trachea.
Images courtesy of the University of New Mexico, College of Pharmacy, and the Lovelace Respiratory Research Institute.
A CT study was performed to quantify the reduction in usable lung capacity in a lizard as a result of gravidity. CT data were acquired late in the gravidity of the lizard and again immediately after the laying of the eggs. Whole-body, six-minute (180 projections/rotation, 1 second per projection) acquisitions were performed in both cases. In the image, the chart displays the quantified change in lung volume (a series of 8-slice, anatomically-based, sub-regions of the lung were used for overall lung volume estimation) as a function of gravidity. The image on the right displays the lung region of the lizard in a gravid state while the imaging the left displays the lung region of the same animal post-gravidity.
Images courtesy of Casey Gilman & Ben Gershman, University of New Mexico
2.6 mCi of In-111 Dotatoc was injected into a 1.5 kg, male rabbit. An 18-minute acquisition was started 5 minutes post injection using an LEUHR collimator on a NanoSPECT/CT. Reconstructions were performed with the Scivis ReSPECT parallel-hole reconstruction software.