A quadruple isotope SPECT/CT imaging acquisition was performed on a rat. 450uCi (17MBq) of Tc99m-MDP, 1.4mCi (52MBq) of I123, 600uCi (22MBq) of In111, and 1mCi (37MBq) of Tl201-Chloride were administered to the rat. A 40-minute image acquisition was performed at 3 hours post-injection of the Tc99m/I123 and 1 hour post-injection of the In111/Tl201. From left to right, the image displays reconstructions of Tc99m (gray; bone uptake), I123 (purple; thyroid and small intestine uptake), In111 (blue; heart, liver, and intestine uptake), and Tl201 (red; kidney, liver, and heart uptake).
Images courtesy of the University of New Mexico College of Pharmacy.
A scout CT scan was collected to pinpoint the heart and liver location in a mouse (maximizing efficiency) injected with Tc99m-labeled MIBI. The animal was anesthetized with sodium pentobarbitol (Nembutol). Focused cardiac-gated (ECG) heart/liver data were acquired with 24 projections collected over an 18mm scan range using 4 apertures equipped with 9 pinholes of 1.4mm diameter (allowing a resolution down to 1.1 mm). Count rates (heart and liver) were approximately 2500 cps. The heart rate was >200 bpm with the cardiac cycle divided into 8 frames.
Special thanks to Dr. Jacob Hesterman for imaging and post-processing, and Dr. Domokos Mathe for the animal handling.
Respiratory gated scan of the torso of a mouse, showing liver, gallbladder and kidneys. Visible are a (M)aximum Intensity Projection, (C)oronal, (S)agittal and (T)ransversal views.
Imaging parameters: 2mCi of Tc99m-labeled MIBI imaged 45 minutes post injection in a 32 minute acquisition.
Special thanks to Ben Gershman and Jacob Hesterman for image acquisition and post-processing.
A rat was injected with ~75 MBq (2 mCi) of Tc-labeled Myoview and imaged 30 minutes post-injection for 1 hour. The rat was anesthetized using Isofluorane and exhibited a stable heart rate of ~250 BPM. Rejection rate was near zero and only a slight decrease in heart rate was observed (and adjusted for) over the course of the acquisition.
Image courtesy of the University of Ottawa Heart Institute.
2.6 mCi of In-111 Dotatoc was injected into a 1.5 kg, male rabbit. An 18-minute acquisition was started 5 minutes post injection using an LEUHR collimator on a NanoSPECT/CT. Reconstructions were performed with the Scivis ReSPECT parallel-hole reconstruction software.
